Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425598 | 0.89 | KMT2A (0.41) | ALDH1A1CTSK | |
| SCHEMBL7424624 | 0.88 | GRN (0.44) | ALDH1A1MAPTRXRARXRBFFAR1 | |
| SCHEMBL7421871 | 0.85 | CTSK (0.48) | ALDH1A1MAPTRXRARXRBCTSS | |
| SCHEMBL7421360 | 0.81 | GPR132 (0.53) | — | |
| SCHEMBL7422327 | 0.79 | GAA (0.47) | MAPTFFAR1GAAHTT | |
| SCHEMBL7423535 | 0.79 | SMN1; SMN2 (0.44) | GAAHTT | |
| SCHEMBL5870561 | 0.79 | ALDH1A1 (0.49) | ALDH1A1PARP10FFAR1 | |
| SCHEMBL5870179 | 0.79 | ALDH1A1 (0.49) | ALDH1A1PARP10FFAR1 | |
| SCHEMBL7417901 | 0.78 | FOLH1 (0.57) | ALDH1A1MAPTCTSSCTSK | |
| SCHEMBL7423140 | 0.78 | CTSS (0.48) | ALDH1A1MAPTFFAR1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |