Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 3/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418995 | 0.93 | CTSL (0.51) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL7412449 | 0.86 | PSMB1 (0.61) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL7418250 | 0.86 | PSMB1 (0.61) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL7420596 | 0.86 | PSMB1 (0.61) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL8623560 | 0.82 | TRPM8 (0.69) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL8163494 | 0.82 | TRPM8 (0.69) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL7415444 | 0.82 | TRPM8 (0.69) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL7418811 | 0.82 | TRPM8 (0.69) | CTSLCTSBTRPM8ALDH1A1ALOX15 | |
| SCHEMBL7417082 | 0.81 | CTSK (0.51) | CTSLCTSBALDH1A1ALOX15CTSS | |
| SCHEMBL7414045 | 0.81 | CTSK (0.51) | CTSLCTSBALDH1A1ALOX15CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |