Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434179 | 0.83 | SLC6A3 (0.49) | SLC6A3DRD2DRD4DRD3CYP1A2 | |
| Hydrochloric Acid SCHEMBL7368184 | 0.78 | TAAR1 (0.67) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5994604 | 0.77 | DRD2 (0.58) | SLC6A3DRD2DRD4DRD3 | |
| SCHEMBL16011858 | 0.75 | DRD2 (0.81) | SLC6A3DRD2DRD4DRD3 | |
| SCHEMBL7433830 | 0.75 | SLC6A2 (0.58) | SLC6A3SLC6A4MPOTAAR1HPGD | |
| SCHEMBL16026371 | 0.73 | SLC6A3 (0.57) | SLC6A3DRD2DRD4DRD3CYP1A2 | |
| SCHEMBL7437721 | 0.72 | SLC6A3 (1.00) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL172293 | 0.72 | TAAR1 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL172536 | 0.71 | TAAR1 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6441045 | 0.71 | DRD2 (0.57) | SLC6A3DRD2DRD4DRD3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171752-A | BENZHYDRYL DERIVATIVES HAVING CALMODULIN INHIBITOR PROPERTIES | AKZO N.V. (NL) | 1992-12-15 | — | — | US | disclosed |
| EP-0467435-A2 | Benzhydryl derivatives having calmodulin inhibitor properties | Akzo Nobel N.V. (NL) | 1992-01-22 | — | — | EP | disclosed |