Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426429 | 0.86 | SIRT2 (0.41) | CTNNB1SIRT2SIRT1EPHX1AURKA | |
| SCHEMBL7694696 | 0.69 | KDM4E (0.47) | MAPK8PPARA | |
| SCHEMBL8211650 | 0.66 | CTNNB1 (0.54) | CTNNB1SIRT2SIRT1AURKARPS6KB1 | |
| SCHEMBL27464948 | 0.65 | CTNNB1 (0.53) | MTNR1ACTNNB1SIRT2SIRT1MAPK8 | |
| SCHEMBL5049439 | 0.64 | CTNNB1 (0.59) | CTNNB1SIRT2SIRT1MAPK8 | |
| SCHEMBL27872615 | 0.63 | CTNNB1 (0.57) | CTNNB1SIRT2SIRT1MAPK8 | |
| SCHEMBL27991301 | 0.63 | CTNNB1 (0.57) | CTNNB1SIRT2SIRT1MAPK8 | |
| SCHEMBL20178657 | 0.63 | EPHX1 (0.47) | SIRT2EPHX1 | |
| SCHEMBL28081509 | 0.62 | BCAT2 (0.61) | CTNNB1SIRT2SIRT1AURKARPS6KB1 | |
| SCHEMBL5175235 | 0.62 | CTNNB1 (0.59) | CTNNB1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073632-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054293-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |