Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423528 | 0.88 | LMNA (0.49) | TRPV1HDAC6HDAC1MEN1KMT2A | |
| SCHEMBL7426638 | 0.87 | ALDH1A1 (0.43) | TRPV1HDAC6HDAC1MEN1KMT2A | |
| SCHEMBL7427033 | 0.84 | GRIA2 (0.43) | TRPV1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7426467 | 0.84 | GRIA2 (0.43) | TRPV1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7425045 | 0.84 | TAS1R3 (0.48) | HDAC6HDAC1MEN1KMT2APTPN1 | |
| SCHEMBL7378945 | 0.84 | MEN1 (0.48) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL7428493 | 0.80 | L3MBTL1 (0.45) | MEN1KMT2ANPC1RAB9APTPN1 | |
| SCHEMBL7418698 | 0.79 | MCHR1 (0.41) | HDAC6HDAC1 | |
| SCHEMBL7417897 | 0.79 | FOLH1 (0.45) | MEN1KMT2AKDM4E | |
| SCHEMBL7423137 | 0.78 | FFAR1 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |