Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 3/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.32 |
| ▸ | ACE | P12821 | 3/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421104 | 0.93 | GRN (0.32) | GRNSORT1ACE2ACENR4A2 | |
| SCHEMBL7425444 | 0.89 | NR4A2 (0.32) | NR4A2 | |
| SCHEMBL7425006 | 0.84 | NR4A2 (0.36) | GRNSORT1NR4A2 | |
| SCHEMBL7429286 | 0.82 | NR4A2 (0.31) | NR4A2 | |
| SCHEMBL7417819 | 0.80 | HDAC1 (0.34) | GRNSORT1ACE2ACE | |
| SCHEMBL7423853 | 0.80 | PPARA (0.35) | GRNSORT1NR4A2 | |
| SCHEMBL7419020 | 0.80 | GRN (0.38) | GRNSORT1ACE2ACE | |
| SCHEMBL7424356 | 0.80 | HDAC1 (0.36) | GRNSORT1ACE2ACE | |
| SCHEMBL7430634 | 0.78 | AOC3 (0.39) | GRNSORT1 | |
| SCHEMBL7419073 | 0.76 | MEN1 (0.33) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |