Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 5/20 | 0.34 |
| ▸ | RXRB | P28702 | 5/20 | 0.34 |
| ▸ | RXRG | P48443 | 5/20 | 0.34 |
| ▸ | GRN | P28799 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417287 | 0.88 | NR4A2 (0.36) | NR4A2RXRARXRBRXRGFOLH1 | |
| SCHEMBL7417310 | 0.86 | NR4A2 (0.44) | NR4A2RXRAFOLH1 | |
| SCHEMBL7419506 | 0.85 | CES1 (0.38) | NR4A2FOLH1 | |
| SCHEMBL7425812 | 0.84 | GRN (0.33) | NR4A2GRNSORT1 | |
| SCHEMBL7423853 | 0.81 | PPARA (0.35) | NR4A2GRNSORT1 | |
| SCHEMBL7426438 | 0.80 | L3MBTL1 (0.34) | NR4A2GRNSORT1 | |
| SCHEMBL7421104 | 0.80 | GRN (0.32) | NR4A2GRNSORT1 | |
| SCHEMBL7419478 | 0.77 | MMP2 (0.42) | RXRARXRBGRNSORT1APP | |
| SCHEMBL7422281 | 0.76 | SHMT1 (0.39) | GRNSORT1 | |
| SCHEMBL7425444 | 0.75 | NR4A2 (0.32) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |