Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428123 | 0.86 | PPARG (0.43) | PPARAFFAR1PPARGNR4A2 | |
| SCHEMBL7421104 | 0.84 | GRN (0.32) | GRNSORT1NR4A2 | |
| SCHEMBL7425006 | 0.81 | NR4A2 (0.36) | GRNSORT1NR4A2 | |
| SCHEMBL7425812 | 0.80 | GRN (0.33) | GRNSORT1NR4A2 | |
| SCHEMBL7422281 | 0.80 | SHMT1 (0.39) | GRNSORT1 | |
| SCHEMBL7419478 | 0.77 | MMP2 (0.42) | PPARAPPARGGRNSORT1 | |
| SCHEMBL7426438 | 0.76 | L3MBTL1 (0.34) | GRNSORT1NR4A2 | |
| SCHEMBL7427310 | 0.74 | CD274 (0.41) | PPARGGRNSORT1NR4A2 | |
| SCHEMBL7429286 | 0.74 | NR4A2 (0.31) | NR4A2 | |
| SCHEMBL7424356 | 0.74 | HDAC1 (0.36) | GRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |