Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717758 | 0.79 | ALDH1A1 (0.47) | ALOX5KMT2AMAPK1SLC6A3NPC1 | |
| SCHEMBL14619236 | 0.78 | FFAR1 (0.50) | ALOX5KMT2A | |
| SCHEMBL9836712 | 0.77 | BCHE (0.49) | ALOX5KDM4AKDM4CKMT2AMAPK1 | |
| SCHEMBL1271129 | 0.76 | ALOX5 (1.00) | ALOX5MAPTRXFP1KDM4AKDM5A | |
| SCHEMBL5320045 | 0.74 | PARP10 (0.44) | ALOX5KMT2AMAPK1SLC6A3NPC1 | |
| SCHEMBL7129964 | 0.73 | ALOX5 (0.66) | ALOX5MAPTRXFP1KDM4AKDM5A | |
| Beloxamide SCHEMBL636320 | 0.73 | L3MBTL1 (0.49) | ALOX5HDAC1HDAC2MAPK1HDAC3 | |
| SCHEMBL386559 | 0.73 | ALOX5 (0.77) | ALOX5MAPTRXFP1KDM4AKDM5A | |
| SCHEMBL9835077 | 0.71 | ALOX5 (1.00) | ALOX5MAPTRXFP1KDM4AKDM5A | |
| SCHEMBL16658765 | 0.71 | ALOX5 (0.75) | ALOX5MAPTRXFP1KDM4AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |