Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17197391 | 0.80 | HTR1A (0.79) | MEN1KMT2AGAAPTGER1PTGER4 | |
| SCHEMBL9080237 | 0.79 | MEN1 (0.83) | MEN1KMT2AGAATRPV1EPHX2 | |
| SCHEMBL2942358 | 0.78 | MEN1 (0.96) | MEN1KMT2AGAATRPV1EPHX2 | |
| Iodide SCHEMBL7715449 | 0.78 | L3MBTL1 (0.58) | MEN1KMT2AGAAHPGDSGMS2 | |
| SCHEMBL10758591 | 0.77 | PTGER1 (0.60) | MEN1KMT2AGAAPTGER1PTGER4 | |
| SCHEMBL7990040 | 0.77 | PTGER1 (0.60) | GAAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7763386 | 0.77 | MEN1 (0.86) | MEN1KMT2AGAATRPV1EPHX2 | |
| SCHEMBL8675521 | 0.77 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2SGMS2 | |
| SCHEMBL2038509 | 0.76 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2MGLL | |
| SCHEMBL10683333 | 0.76 | HTR1A (0.67) | MEN1KMT2AGAAPTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |