Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | KLK1 | P06870 | 2/20 | 0.54 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426358 | 0.87 | KMT2A (0.58) | NR1H4KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL7433371 | 0.85 | NR1H4 (1.00) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL19248291 | 0.82 | KMT2A (0.73) | KMT2AKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL13451640 | 0.81 | MEN1 (0.73) | NR1H4KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL7425090 | 0.79 | SLC16A3 (0.59) | NR1H4KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8133663 | 0.79 | RAB9A (1.00) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL14048607 | 0.78 | RAB9A (0.58) | NR1H4KMT2AKDM4ERAB9AMEN1 | |
| SCHEMBL26889396 | 0.78 | DEGS1 (0.79) | NR1H4KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL31150345 | 0.78 | DEGS1 (0.78) | NR1H4KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL368228 | 0.78 | DEGS1 (0.78) | NR1H4KMT2AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |