Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SELL | P14151 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | HNF4A | P41235 | 3/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026199 | 0.85 | SELL (0.57) | KDM4EALDH1A1HPGDSELLSELP | |
| SCHEMBL31509453 | 0.85 | SELL (0.57) | KDM4EALDH1A1HPGDSELLSELP | |
| SCHEMBL4151580 | 0.84 | BCAT2 (0.59) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6389902 | 0.80 | BCAT2 (0.47) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1286775 | 0.80 | MEN1 (0.51) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL926679 | 0.80 | KDM4E (0.52) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3870477 | 0.79 | KDM4E (0.61) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL27214460 | 0.78 | BCAT2 (0.63) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4286154 | 0.77 | ALOX5 (0.38) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL28562251 | 0.76 | BCAT2 (0.47) | BCAT2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068187-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051580-A1 | PYRAZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES (US) | 1999-10-14 | — | — | WO | disclosed |