Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423500 | 0.80 | L3MBTL1 (0.38) | RAB9AMAPTL3MBTL1 | |
| SCHEMBL6424261 | 0.77 | HTT (0.40) | RAB9AMEN1KMT2A | |
| SCHEMBL740751 | 0.76 | HPGD (0.44) | RAB9AHPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14737095 | 0.74 | GRM3 (0.44) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5554898 | 0.74 | RAB9A (0.72) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5554906 | 0.74 | RAB9A (0.72) | RAB9AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL193002 | 0.72 | ALDH1A1 (0.49) | RAB9AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4678821 | 0.72 | GLA (0.52) | RAB9AMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL2595616 | 0.72 | PDK2 (0.36) | RAB9AMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL4099888 | 0.72 | RAB9A (0.57) | RAB9AMAPTHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |