Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440995 | 0.86 | ATM (0.43) | ATMPOLBNPSR1ACECNR2 | |
| SCHEMBL7441051 | 0.82 | ATM (0.37) | ATMPOLBNPSR1ACECNR2 | |
| SCHEMBL7426767 | 0.79 | ACE (0.37) | ACEMME | |
| SCHEMBL7428792 | 0.71 | CYP2D6 (0.45) | POLBNPSR1ACEMME | |
| SCHEMBL7436241 | 0.70 | ACE (0.42) | POLBACE | |
| SCHEMBL7432273 | 0.69 | AMPD2 (0.37) | POLBNPSR1 | |
| SCHEMBL7434091 | 0.69 | ACE (0.41) | POLBACE | |
| SCHEMBL7433475 | 0.69 | SIGMAR1 (0.44) | ACEMME | |
| SCHEMBL7443207 | 0.68 | ACE (0.41) | ACE | |
| SCHEMBL7439237 | 0.68 | ACE (0.41) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |