Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 8/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.54 |
| ▸ | CHRNA5 | P30532 | 3/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433128 | 0.89 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CHRNA5CHRM3 | |
| SCHEMBL7438953 | 0.85 | RAB9A (0.44) | KMT2ARAB9A | |
| SCHEMBL7435418 | 0.82 | NPSR1 (0.50) | KMT2ATSHRRAB9A | |
| SCHEMBL7440850 | 0.80 | MAPT (0.60) | KMT2ATSHRRAB9A | |
| SCHEMBL7434975 | 0.79 | RAB9A (0.63) | KMT2ARAB9A | |
| SCHEMBL7433322 | 0.78 | ALDH1A1 (0.58) | KMT2ARAB9A | |
| SCHEMBL7425411 | 0.76 | KMT2A (0.52) | KMT2ATSHRRAB9A | |
| SCHEMBL7435298 | 0.76 | RAB9A (0.49) | RAB9A | |
| SCHEMBL7430630 | 0.76 | RAB9A (0.48) | RAB9A | |
| SCHEMBL7434594 | 0.75 | RAB9A (0.47) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |