Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660210 | 0.86 | KIF11 (0.38) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL864054 | 0.76 | KCNN4 (0.41) | CYP2C19CYP1A2CYP2C9KIF11SMN1; SMN2 | |
| SCHEMBL19730614 | 0.75 | TDP1 (0.40) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL29097001 | 0.75 | TDP1 (0.40) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL913229 | 0.75 | KIF11 (0.54) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL19614367 | 0.73 | KCNN4 (0.48) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL301346 | 0.73 | SMN1; SMN2 (0.55) | CYP2C19CYP1A2CYP2C9KIF11SMN1; SMN2 | |
| SCHEMBL11212708 | 0.73 | CYP2C19 (0.43) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL12727017 | 0.73 | CYP1A2 (0.54) | TDP1CYP2C19CYP1A2CYP2C9KIF11 | |
| SCHEMBL4194598 | 0.73 | KIF11 (0.38) | KIF11SMN1; SMN2TSHRALDH1A1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091142-A1 | Alpha4beta1 and alpha4beta7 integrin inhibitors | COOKE NIGEL GRAHAM (US) | 2002-07-11 | — | — | US | disclosed |
| WO-2001068586-A2 | α4β1 AND α4β7 INTEGRIN INHIBITORS | NOVARTIS AG (CH) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091142-A1 | Alpha4beta1 and alpha4beta7 integrin inhibitors | ITGB1, ITGB4, ITGB7 | TDP1 3566/4885CYP2C19 1781/4885CYP1A2 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.