Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447128 | 0.91 | RAB9A (0.52) | HTTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7443888 | 0.90 | POLB (0.48) | HTTLMNAALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL7433767 | 0.90 | DRD4 (0.53) | DRD4DRD2DRD3ALDH1A1RAB9A | |
| SCHEMBL7436242 | 0.90 | LMNA (0.46) | HTTLMNAGAADRD4DRD2 | |
| SCHEMBL7428126 | 0.89 | ALDH1A1 (0.48) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7434584 | 0.89 | ALDH1A1 (0.47) | HTTLMNAGAADRD4DRD2 | |
| SCHEMBL10995044 | 0.87 | ALDH1A1 (0.48) | HTTLMNAGAADRD4DRD2 | |
| SCHEMBL7444058 | 0.87 | ALDH1A1 (0.44) | HTTLMNAGAADRD4DRD2 | |
| SCHEMBL7439962 | 0.86 | ALDH1A1 (0.47) | HTTLMNAGAADRD4DRD2 | |
| SCHEMBL7437024 | 0.86 | LMNA (0.45) | HTTLMNAGAADRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |