Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.80 |
| ▸ | MMP9 | P14780 | 16/20 | 0.80 |
| ▸ | MMP2 | P08253 | 16/20 | 0.80 |
| ▸ | MMP3 | P08254 | 15/20 | 0.80 |
| ▸ | MMP8 | P22894 | 10/20 | 0.80 |
| ▸ | MMP7 | P09237 | 10/20 | 0.67 |
| ▸ | MMP13 | P45452 | 5/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP15 | P51511 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312415 | 0.89 | MMP1 (1.00) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7483182 | 0.87 | MMP1 (0.79) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7480347 | 0.86 | MMP2 (0.81) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7480352 | 0.86 | MMP2 (0.81) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7479388 | 0.86 | MMP1 (0.75) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7246059 | 0.79 | MMP3 (0.51) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7245645 | 0.79 | MMP1 (0.51) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7214256 | 0.77 | MMP1 (0.60) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL7058353 | 0.77 | MMP1 (0.69) | MMP1MMP9MMP2MMP3MMP8 | |
| SCHEMBL8379941 | 0.77 | MMP1 (0.48) | MMP1MMP9MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923561-B1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | disclosed |
| US-6399598-B1 | ORAL DISEASES; RHEUMATIC DISEASES; OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY | 2002-06-04 | — | — | US | disclosed |
| US-6121258-A | FOR TREATMENT OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS, SKIN DISORDERS, OCULAR DISORDERS, INFLAMMATION, GUM DISEASE | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0923561-A1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008823-A1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |