Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.81 |
| ▸ | MMP1 | P03956 | 10/20 | 0.81 |
| ▸ | MMP9 | P14780 | 10/20 | 0.81 |
| ▸ | MMP3 | P08254 | 10/20 | 0.81 |
| ▸ | MMP8 | P22894 | 9/20 | 0.81 |
| ▸ | MMP7 | P09237 | 6/20 | 0.68 |
| ▸ | MMP13 | P45452 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480352 | 1.00 | MMP2 (0.81) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL7483182 | 0.92 | MMP1 (0.79) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL4312415 | 0.90 | MMP1 (1.00) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL7479388 | 0.89 | MMP1 (0.75) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL7428159 | 0.86 | MMP1 (0.80) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL7664941 | 0.84 | MMP2 (0.60) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL5639168 | 0.77 | MMP1 (0.61) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL6608718 | 0.76 | MMP1 (0.60) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL7480845 | 0.76 | MMP1 (0.58) | MMP2MMP1MMP9MMP3MMP8 | |
| SCHEMBL5636276 | 0.76 | MMP1 (0.73) | MMP2MMP1MMP9MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923561-B1 | HETEROCYCLIC METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | disclosed |
| US-6399598-B1 | ORAL DISEASES; RHEUMATIC DISEASES; OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY | 2002-06-04 | — | — | US | disclosed |
| US-6121258-A | FOR TREATMENT OF ARTHRITIS, CANCER, CARDIOVASCULAR DISORDERS, SKIN DISORDERS, OCULAR DISORDERS, INFLAMMATION, GUM DISEASE | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |