SCHEMBL4312415

SCHEMBL4312415

COc1ccc(S(=O)(=O)N2CN(Cc3ccccc3)C(=O)CC2C(=O)NO)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 19/20 1.00
MMP3 P08254 18/20 1.00
MMP9 P14780 15/20 1.00
MMP2 P08253 13/20 1.00
MMP8 P22894 10/20 1.00
MMP7 P09237 13/20 0.84
MMP13 P45452 7/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7480347 0.90 MMP2 (0.81) MMP1MMP3MMP9MMP2MMP8
SCHEMBL7480352 0.90 MMP2 (0.81) MMP1MMP3MMP9MMP2MMP8
SCHEMBL7428159 0.89 MMP1 (0.80) MMP1MMP3MMP9MMP2MMP8
SCHEMBL7483182 0.88 MMP1 (0.79) MMP1MMP3MMP9MMP2MMP8
SCHEMBL7479388 0.85 MMP1 (0.75) MMP1MMP3MMP9MMP2MMP8
SCHEMBL5636276 0.84 MMP1 (0.73) MMP1MMP3MMP9MMP2MMP8
SCHEMBL18313867 0.79 MMP1 (1.00) MMP1MMP3MMP9MMP2MMP8
SCHEMBL27547262 0.78 MMP1 (0.74) MMP1MMP3MMP9MMP2MMP8
SCHEMBL8379577 0.77 MMP3 (0.62) MMP1MMP3MMP9MMP2MMP8
SCHEMBL5639168 0.76 MMP1 (0.61) MMP1MMP3MMP9MMP2MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20200278346-A1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ADJACENT ACQUISITION CO., LLC 2020-09-03 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed