Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417901 | 0.80 | FOLH1 (0.57) | FPR2ALDH1A1LMNAMAPTCTSS | |
| SCHEMBL7378949 | 0.80 | MME (0.50) | ALDH1A1LMNACTSSFOLH1 | |
| SCHEMBL7423166 | 0.80 | NPSR1 (0.49) | FPR2LMNAMAPTPTPN1RAB9A | |
| SCHEMBL7425540 | 0.80 | DGAT1 (0.47) | ALDH1A1LMNAPTPN1NPC1HTT | |
| SCHEMBL7427045 | 0.78 | GRIA2 (0.52) | FPR2ALDH1A1LMNAMAPTCTSL | |
| SCHEMBL7426474 | 0.78 | GRIA2 (0.52) | FPR2ALDH1A1LMNAMAPTCTSL | |
| SCHEMBL7424801 | 0.77 | CTSS (0.46) | ALDH1A1CTSLCTSSFOLH1SMN1; SMN2 | |
| SCHEMBL7425607 | 0.76 | CTSL (0.48) | CTSLCTSSFOLH1 | |
| SCHEMBL7418370 | 0.76 | PSEN1 (0.60) | CTSLCTSS | |
| SCHEMBL8258429 | 0.75 | FOLH1 (0.49) | L3MBTL1FPR2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |