Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.43 |
| ▸ | KDM5A | P29375 | 5/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27285942 | 0.85 | KDM5A (0.49) | DHODHKEAP1KDM5BKDM5AMTNR1A | |
| SCHEMBL7414885 | 0.83 | MTNR1A (0.46) | DAOKDM4EMAPTPIM1NR4A2 | |
| SCHEMBL10990305 | 0.83 | KDM5A (0.47) | DHODHKDM5BKDM5APARP1 | |
| SCHEMBL10982575 | 0.83 | KDM5A (0.47) | DHODHKDM5BKDM5APARP1 | |
| SCHEMBL10981682 | 0.83 | KDM5A (0.47) | DHODHKDM5BKDM5APARP1 | |
| SCHEMBL7648523 | 0.81 | KDM5B (0.60) | DHODHKEAP1KDM5BKDM5AKDM4E | |
| SCHEMBL2078975 | 0.78 | DHODH (0.58) | DHODHKEAP1DAOKDM4EMAPT | |
| SCHEMBL7428568 | 0.78 | KDM4E (0.52) | DHODHKEAP1KDM5BKDM5AKDM4E | |
| SCHEMBL5185975 | 0.76 | ALDH1A1 (0.39) | DHODHKDM5BKDM5AKDM4EKDM4C | |
| SCHEMBL11035155 | 0.76 | HSD17B10 (0.62) | DHODHKEAP1DAOKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041717-A1 | N-((3-BENZYL)-2,2-(BIS-PHENYL)-PROPAN-1-AMINE DERIVATIVES AS CETP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-18 | — | — | US | disclosed |
| CN-101076531-A | Carboxylic acid peri-substituted bicyclics for occlusive artery disease | DECODE CHEMISTRY INC (US) | 2007-11-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041717-A1 | N-((3-BENZYL)-2,2-(BIS-PHENYL)-PROPAN-1-AMINE DERIVATIVES AS CETP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASES | CETP, APOB, CES1 | DHODH 3559/4885KEAP1 1899/4885KDM5B 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.