Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425049 | 0.81 | HDAC1 (0.40) | GLSNAMPTL3MBTL1BRD4CREBBP | |
| SCHEMBL7129747 | 0.78 | HDAC1 (0.42) | GLSNAMPTL3MBTL1BRD4CREBBP | |
| SCHEMBL7435753 | 0.74 | HDAC1 (0.40) | GLSNAMPTL3MBTL1BRD4CREBBP | |
| SCHEMBL17171456 | 0.73 | GPR119 (0.46) | GLSNAMPTL3MBTL1HDAC1GAA | |
| SCHEMBL7435220 | 0.72 | NAMPT (0.42) | GLSNAMPTL3MBTL1BRD4CREBBP | |
| SCHEMBL7129744 | 0.70 | NAMPT (0.41) | GLSNAMPTL3MBTL1BRD4CREBBP | |
| SCHEMBL13055397 | 0.70 | KDM4A (0.51) | GLSNAMPTL3MBTL1HDAC1GAA | |
| SCHEMBL3180689 | 0.70 | L3MBTL1 (0.61) | NAMPTL3MBTL1HDAC1FPR3FPR2 | |
| SCHEMBL24619900 | 0.69 | IGF1R (0.48) | GLSNAMPTL3MBTL1BRD4CREBBP | |
| SCHEMBL15486014 | 0.69 | L3MBTL1 (0.42) | GLSNAMPTL3MBTL1BRD4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |