Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17171456 | 0.77 | GPR119 (0.46) | NAMPTL3MBTL1GLSGAAKDM4A | |
| SCHEMBL7438342 | 0.75 | SMN1; SMN2 (0.48) | NAMPTL3MBTL1GLSGAAKDM4A | |
| SCHEMBL3180689 | 0.74 | L3MBTL1 (0.61) | NAMPTL3MBTL1GAAKDM4AHDAC1 | |
| SCHEMBL15486014 | 0.73 | L3MBTL1 (0.42) | NAMPTL3MBTL1GLSGAAKDM4A | |
| SCHEMBL7428709 | 0.72 | GLS (0.39) | NAMPTL3MBTL1GLSGAAKDM4A | |
| SCHEMBL13055397 | 0.71 | KDM4A (0.51) | NAMPTL3MBTL1GLSGAAKDM4A | |
| SCHEMBL5749285 | 0.71 | ERCC1 (0.56) | NAMPTL3MBTL1GAAHDAC1CA1 | |
| SCHEMBL14907948 | 0.70 | GAA (0.52) | NAMPTL3MBTL1GLSGAAKDM4A | |
| SCHEMBL30193348 | 0.70 | NLRP3 (0.52) | NAMPTL3MBTL1GAAKDM4AGRM2 | |
| SCHEMBL1615764 | 0.70 | NLRP3 (0.52) | NAMPTL3MBTL1GAAKDM4AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | disclosed |