Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SRPK1 | Q96SB4 | 7/20 | 0.37 |
| ▸ | SRPK2 | P78362 | 5/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.36 |
| ▸ | EML4 | Q9HC35 | 5/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435163 | 0.85 | MEN1 (0.50) | MEN1KMT2ASRPK1SRPK2CYP2A6 | |
| SCHEMBL7447629 | 0.85 | MEN1 (0.50) | MEN1KMT2ASRPK1SRPK2CYP2A6 | |
| SCHEMBL22417805 | 0.85 | MEN1 (0.69) | MEN1KMT2ASRPK1SRPK2CYP2A6 | |
| SCHEMBL7451903 | 0.77 | MEN1 (0.49) | MEN1KMT2ASRPK1SRPK2ALK | |
| SCHEMBL7443194 | 0.74 | SLC6A4 (0.56) | MEN1KMT2AALK | |
| SCHEMBL7452517 | 0.73 | SLC6A4 (0.56) | MEN1KMT2AALK | |
| SCHEMBL28588337 | 0.72 | PIN1 (0.45) | MEN1KMT2ASRPK1SRPK2ALK | |
| SCHEMBL6007662 | 0.72 | CHUK (0.53) | MEN1KMT2ACYP2A6MAPK10RIPK1 | |
| SCHEMBL7570580 | 0.72 | HTR6 (0.48) | ALK | |
| SCHEMBL9182077 | 0.70 | NOS3 (0.42) | MEN1KMT2ASRPK1SRPK2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012600-A9 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC (US) | 2002-09-12 | — | — | WO | disclosed |
| WO-2001012600-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |