Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SRPK1 | Q96SB4 | 5/20 | 0.37 |
| ▸ | SRPK2 | P78362 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.36 |
| ▸ | EML4 | Q9HC35 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22417805 | 0.85 | MEN1 (0.69) | MEN1KMT2ASRPK1SRPK2SLC6A4 | |
| SCHEMBL7435163 | 0.85 | MEN1 (0.50) | MEN1KMT2ASRPK1SRPK2CYP2A6 | |
| SCHEMBL7428870 | 0.85 | MEN1 (0.50) | MEN1KMT2ASRPK1SRPK2CYP2A6 | |
| SCHEMBL7451903 | 0.77 | MEN1 (0.49) | MEN1KMT2ASRPK1SRPK2SLC6A4 | |
| SCHEMBL7443194 | 0.74 | SLC6A4 (0.56) | MEN1KMT2ASLC6A4ALK | |
| SCHEMBL7452517 | 0.73 | SLC6A4 (0.56) | MEN1KMT2ASLC6A4ALK | |
| SCHEMBL28588337 | 0.72 | PIN1 (0.45) | MEN1KMT2ASRPK1SRPK2ALK | |
| SCHEMBL6007662 | 0.72 | CHUK (0.53) | MEN1KMT2ACYP2A6MAPK10RIPK1 | |
| SCHEMBL7570580 | 0.72 | HTR6 (0.48) | ALK | |
| SCHEMBL9182077 | 0.70 | NOS3 (0.42) | MEN1KMT2ASRPK1SRPK2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |