Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944811 | 0.78 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7427141 | 0.76 | HTR3A (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21800234 | 0.73 | MAPT (0.42) | ALDH1A1MAPTPKM | |
| SCHEMBL7429437 | 0.72 | KMT2A (0.65) | MEN1KMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL5388810 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7376264 | 0.71 | LGMN (0.40) | KMT2ALMNAALDH1A1RAB9AMAPT | |
| SCHEMBL1740752 | 0.71 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5922625 | 0.71 | ALDH1A1 (0.46) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7434944 | 0.71 | HTR3A (0.42) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2709699 | 0.69 | HTR3A (0.63) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256665-A | Process for preparing new 2-piperazinylbenzimidazole | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1993-10-26 | — | — | US | claimed |
| EP-0512939-A1 | New 2-piperazinylbenzimidazole derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-11-11 | — | — | EP | claimed |
| EP-0512939-B1 | 2-piperazinylbenzimidazole derivatives | ESPANOLA PROD QUIMICOS (ES) | 1999-08-25 | — | — | EP | disclosed |
| US-5256665-A | Process for preparing new 2-piperazinylbenzimidazole | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1993-10-26 | — | — | US | disclosed |
| EP-0512939-A1 | New 2-piperazinylbenzimidazole derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-11-11 | — | — | EP | disclosed |