Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936977 | 0.85 | SLC6A2 (0.40) | OPRK1SLC6A4SLC6A2CETPFFAR1 | |
| SCHEMBL6940292 | 0.81 | SLC6A4 (0.34) | SLC6A4SLC6A2CETPPTGS1OPRM1 | |
| SCHEMBL6940376 | 0.80 | SLC6A4 (0.36) | OPRK1SLC6A4SLC6A2CETPFFAR1 | |
| SCHEMBL7429944 | 0.78 | CETP (0.36) | SLC6A4SLC6A2CETPPTGS1OPRM1 | |
| SCHEMBL5164050 | 0.76 | CCR5 (0.38) | SLC6A4OPRM1KDRSLC6A3 | |
| SCHEMBL6936254 | 0.75 | C3AR1 (0.37) | SLC6A4OPRM1KDRSLC6A3 | |
| SCHEMBL5162722 | 0.75 | SLC6A2 (0.45) | OPRK1SLC6A4SLC6A2OPRM1SLC6A3 | |
| SCHEMBL6936755 | 0.75 | SLC6A2 (0.47) | OPRK1SLC6A4SLC6A2OPRM1 | |
| SCHEMBL5158039 | 0.74 | MEN1 (0.40) | OPRK1L3MBTL1OPRM1 | |
| Hydrochloric Acid SCHEMBL5845093 | 0.74 | SLC6A2 (0.44) | OPRK1SLC6A4SLC6A2OPRM1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |