Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429939 | 0.78 | OPRK1 (0.34) | CETPPTGS1SLC6A4OPRM1KDR | |
| SCHEMBL6936977 | 0.77 | SLC6A2 (0.40) | CETPSLC6A4OPRM1SLC6A3SLC6A2 | |
| SCHEMBL6940376 | 0.77 | SLC6A4 (0.36) | CETPPTGS1SLC6A4OPRM1KDR | |
| SCHEMBL6940292 | 0.75 | SLC6A4 (0.34) | CETPPTGS1SLC6A4OPRM1KDR | |
| SCHEMBL6676441 | 0.69 | SLC6A2 (0.45) | SLC6A4OPRM1SLC6A3SLC6A2MEN1 | |
| SCHEMBL5160480 | 0.68 | SLC6A4 (0.58) | SLC6A4OPRM1SLC6A2MEN1KMT2A | |
| SCHEMBL11621996 | 0.67 | SLC6A4 (0.41) | SLC6A4OPRM1KDRSLC6A3SLC6A2 | |
| SCHEMBL6939049 | 0.67 | ALDH1A1 (0.45) | PTGS1SLC6A4OPRM1KDRSLC6A3 | |
| SCHEMBL6936755 | 0.67 | SLC6A2 (0.47) | SLC6A4OPRM1SLC6A2MEN1KMT2A | |
| SCHEMBL5164176 | 0.66 | SLC6A2 (0.44) | SLC6A4OPRM1SLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |