Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425597 | 0.90 | PLK1 (0.57) | PLK1ALDH1A1POLBRAB9AMAPT | |
| SCHEMBL7440946 | 0.86 | ALDH1A1 (0.53) | PLK1ALDH1A1POLBRAB9AMAPT | |
| SCHEMBL7631396 | 0.81 | L3MBTL1 (0.67) | L3MBTL1PLK1ALDH1A1POLBRAB9A | |
| SCHEMBL19234514 | 0.78 | KMT2A (0.61) | PLK1ALDH1A1POLBRAB9AMAPT | |
| SCHEMBL7444387 | 0.78 | RAB9A (0.55) | L3MBTL1ALDH1A1POLBRAB9AMAPT | |
| SCHEMBL6845396 | 0.78 | KDM4E (0.72) | PLK1ALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL7436867 | 0.78 | HSD17B3 (0.52) | L3MBTL1ALDH1A1POLBRAB9AMAPT | |
| SCHEMBL12840799 | 0.78 | ALDH1A1 (0.51) | L3MBTL1PLK1ALDH1A1POLBRAB9A | |
| SCHEMBL30089521 | 0.77 | L3MBTL1 (0.85) | L3MBTL1PLK1ALDH1A1POLBRAB9A | |
| SCHEMBL10021819 | 0.77 | L3MBTL1 (0.67) | L3MBTL1PLK1ALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |