Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891503 | 1.00 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL364908 | 0.97 | — | — | |
| SCHEMBL5010340 | 0.80 | L3MBTL3 (0.45) | L3MBTL1ALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL6202425 | 0.78 | L3MBTL3 (0.44) | L3MBTL1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL21798768 | 0.78 | HTT (0.48) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL28385713 | 0.77 | CA12 (0.35) | HTT | |
| SCHEMBL34638 | 0.76 | HTT (0.52) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL3158910 | 0.76 | HTT (0.47) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL9727085 | 0.76 | HTT (0.52) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL365772 | 0.75 | EPHX2 (0.53) | HTTLIPEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362174-B1 | ANALGESICS, ANTIISCHEMIC AGENTS, ANTIEOILEPTIC AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-20020028801-A1 | Reduced dipeptide analogues as calcium channel antagonitsts | RAFFERTY MICHAEL FRANCIS (US) | 2002-03-07 | — | — | US | disclosed |
| US-6316440-B1 | TREATMENT OF STROKE, HEAD TRAUMA, CEREBRAL ISCHEMIA, PAIN AND EPILEPSY | WARNER-LAMBERT COMPANY | 2001-11-13 | — | — | US | disclosed |
| WO-2000006559-A1 | REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0220034-B1 | MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0219332-B1 | TARTRATE COMPOUNDS USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4851461-A | PHOTOSTABILIZERS | ICI AMERICAS INC. (US) | 1989-07-25 | — | — | US | disclosed |
| US-4804699-A | Monomeric and oligomeric glutarate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0291238-A2 | Monomeric and oligomeric glutarate-based light stabilisers for plastics | ICI AMERICAS INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| US-4710527-A | STERICALLY HINDERED SPIROACETALS OF POLYALKYLPIPERIDIN-4-ONES | ICI AMERICAS INC. (US) | 1987-12-01 | — | — | US | disclosed |
| US-4701485-A | Malonate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-10-20 | — | — | US | disclosed |
| US-4690963-A | POLYALKYL-1,4-DIOXA-8-AZASPIRO(4.5)DECANE-2,3-DICARBOXYLIC ACIDS, ESTERS OR AMIDES; POLYPROPYLENE FILMS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4689360-A | SPIRO RING CONTAINING ESTERS | ICI AMERICAS INC. (US) | 1987-08-25 | — | — | US | disclosed |
| US-4687800-A | POLYALKYL PIPERIDIN-4-YL CONTAINING ACETAL ESTERS AND AMIDES | ICI AMERICAS INC. (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0222512-A2 | Malonate compounds useful as light stabilizers for plastics | CYTEC TECHNOLOGY CORP. (US) | 1987-05-20 | — | — | EP | disclosed |
| EP-0220034-A2 | Malonate derivatives useful as light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-04-29 | — | — | EP | disclosed |
| EP-0219332-A2 | Tartrate compounds useful as light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028801-A1 | Reduced dipeptide analogues as calcium channel antagonitsts | CACNA1E, RYR1, CACNA1B | HTT 1142/4885LIPE 4607/4885L3MBTL1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.