Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430647 | 1.00 | HTT (0.45) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL364908 | 0.97 | — | — | |
| SCHEMBL5010340 | 0.80 | L3MBTL3 (0.45) | L3MBTL1ALDH1A1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL6202425 | 0.78 | L3MBTL3 (0.44) | L3MBTL1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL21798768 | 0.78 | HTT (0.48) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL28385713 | 0.77 | CA12 (0.35) | HTT | |
| SCHEMBL34638 | 0.76 | HTT (0.52) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL3158910 | 0.76 | HTT (0.47) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL9727085 | 0.76 | HTT (0.52) | HTTLIPEL3MBTL1LMNAPOLB | |
| SCHEMBL365772 | 0.75 | EPHX2 (0.53) | HTTLIPEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628045-B1 | COMPOUNDS | UNIV SHEFFIELD (GB) | 2024-07-03 | — | — | EP | disclosed |
| EP-3533785-B1 | PENTAMETHYLENE DIISOCYANATE PRODUCTION METHOD | MITSUI CHEMICALS INC (JP) | 2023-11-29 | — | — | EP | disclosed |
| CN-109415307-B | Process for producing pentamethylene diisocyanate | 三井化学株式会社 | 2021-06-04 | — | — | CN | disclosed |
| US-20210113534-A1 | COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2021-04-22 | — | — | US | disclosed |
| EP-3628045-A1 | COMPOUNDS | The University Of Sheffield (GB) | 2020-04-01 | — | — | EP | disclosed |
| CN-110891951-A | Compound (I) | 谢菲尔德大学 | 2020-03-17 | — | — | CN | disclosed |
| US-10238677-B2 | Treatment of filarial diseases | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2019-03-26 | — | — | US | disclosed |
| CN-109415307-A | The manufacturing method of pentamethylene diisocyanate | 三井化学株式会社 | 2019-03-01 | — | — | CN | disclosed |
| WO-2018211275-A1 | COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2018-11-22 | — | — | WO | disclosed |
| US-10072040-B2 | Tylosin A analogs and derivatives | ABBVIE INC. (US) | 2018-09-11 | — | — | US | disclosed |
| US-4507291-A | Arthropod repellents | ROHM AND HAAS COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| US-4451278-A | 1-Hydroxyanthraquinone aquatic herbicide | GAF CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4405630-A | AZASPIRO COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| US-4400512-A | INSECT REPELLENTS | ROHM AND HAAS COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| US-4374991-A | INSECT REPELLENTS | ROHM AND HAAS COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| US-4357471-A | INSECT REPELLENTS | ROHM AND HAAS COMPANY (US) | 1982-11-02 | — | — | US | disclosed |
| US-4252943-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1981-02-24 | — | — | US | disclosed |
| US-4217359-A | HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4101571-A | REACTING SULFAMIC ACIDS WITH PHOSGENE | BASF AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-3947594-A | 4-Halo-1-hydroxyanthraquinone containing fungicidal composition | GAF CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10238677-B2 | Treatment of filarial diseases | LTA, PPT1, LTA4H | HTT 342/4885LIPE 174/4885L3MBTL1 316/4885 |
| US-20210113534-A1 | COMPOUNDS | MRGPRX2, MC2R, ADM2 | HTT 4017/4885LIPE 1893/4885L3MBTL1 3736/4885 |
| US-10072040-B2 | Tylosin A analogs and derivatives | TXLNA, TMSB4X, TMSB10 | HTT 5/4885LIPE 508/4885L3MBTL1 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.