Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439371 | 0.89 | LMNA (0.42) | KDM4EALDH1A1LTA4HMAPTMAPK1 | |
| SCHEMBL7438055 | 0.87 | GAA (0.42) | GAAKDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7436670 | 0.86 | NPC1 (0.44) | LTA4HMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL7435319 | 0.86 | EPHX1 (0.47) | ALDH1A1LTA4HMAPTMAPK1LMNA | |
| SCHEMBL7441435 | 0.86 | L3MBTL1 (0.43) | GAAKDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7431782 | 0.85 | SMN1; SMN2 (0.44) | GAAKDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7431583 | 0.84 | POLB (0.42) | GAAKDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7431578 | 0.84 | POLB (0.42) | GAAKDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7432498 | 0.84 | LTA4H (0.52) | GAAKDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7432553 | 0.83 | MAPT (0.47) | GAAKDM4EALDH1A1LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |