Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435319 | 0.92 | EPHX1 (0.47) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7438480 | 0.90 | LMNA (0.44) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7438375 | 0.90 | DRD3 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7440526 | 0.88 | GAA (0.46) | NPC1RAB9ASMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL7435567 | 0.88 | TEAD1 (0.46) | TSHRMGLLMEN1KMT2AEPHX2 | |
| SCHEMBL7434127 | 0.87 | ALOX5 (0.47) | NPC1TSHRRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7438639 | 0.87 | ALDH1A1 (0.47) | NPC1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7430833 | 0.86 | GAA (0.43) | NPC1SMN1; SMN2KMT2ALTA4HMAPT | |
| SCHEMBL7432904 | 0.86 | LTA4H (0.44) | SMN1; SMN2MGLLKMT2ALTA4HMAPT | |
| SCHEMBL7431389 | 0.85 | HPGD (0.51) | TSHRSMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |