Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438480 | 0.92 | LMNA (0.44) | LTA4HDRD4DRD2DRD3MAPT | |
| SCHEMBL7436670 | 0.92 | NPC1 (0.44) | LTA4HMAPTSMN1; SMN2EPHX2PRMT5 | |
| SCHEMBL7438375 | 0.92 | DRD3 (0.49) | LTA4HDRD4DRD2DRD3SMN1; SMN2 | |
| SCHEMBL7435567 | 0.90 | TEAD1 (0.46) | EPHX1LTA4HEPHX2PRMT5HPGD | |
| SCHEMBL7440526 | 0.90 | GAA (0.46) | SMN1; SMN2EPHX2LMNAALDH1A1ACHE | |
| SCHEMBL7438639 | 0.88 | ALDH1A1 (0.47) | SMN1; SMN2CYP2C19ALDH1A1NPC1HPGD | |
| SCHEMBL7432498 | 0.87 | LTA4H (0.52) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7432904 | 0.87 | LTA4H (0.44) | LTA4HDRD4MAPTSMN1; SMN2LMNA | |
| SCHEMBL7431389 | 0.86 | HPGD (0.51) | MAPTSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL7431782 | 0.86 | SMN1; SMN2 (0.44) | LTA4HMAPTSMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |