Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.49 |
| ▸ | MMP9 | P14780 | 17/20 | 0.49 |
| ▸ | MMP1 | P03956 | 11/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421799 | 0.90 | MMP9 (0.52) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7434872 | 0.88 | MMP9 (0.52) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7426328 | 0.81 | MMP2 (0.40) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7595400 | 0.81 | MMP9 (0.74) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7595412 | 0.81 | MMP9 (0.74) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7483524 | 0.75 | MMP9 (0.66) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7595406 | 0.73 | MMP9 (0.47) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7421796 | 0.70 | MMP1 (0.43) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7595948 | 0.70 | MMP9 (0.80) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL7595943 | 0.70 | MMP9 (0.80) | MMP2MMP9MMP1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000044739-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |