Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.40 |
| ▸ | MMP3 | P08254 | 9/20 | 0.40 |
| ▸ | MMP9 | P14780 | 8/20 | 0.40 |
| ▸ | MMP1 | P03956 | 7/20 | 0.40 |
| ▸ | MMP13 | P45452 | 7/20 | 0.40 |
| ▸ | MMP7 | P09237 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421796 | 0.90 | MMP1 (0.43) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7434867 | 0.89 | MMP9 (0.43) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7430869 | 0.81 | MMP2 (0.49) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7595406 | 0.80 | MMP9 (0.47) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7595400 | 0.73 | MMP9 (0.74) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7595412 | 0.73 | MMP9 (0.74) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7434872 | 0.70 | MMP9 (0.52) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7421799 | 0.70 | MMP9 (0.52) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7595945 | 0.69 | MMP9 (0.51) | MMP2MMP3MMP9MMP1MMP13 | |
| SCHEMBL7430861 | 0.69 | MMP2 (0.41) | MMP2MMP3MMP9MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000044739-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |
| EP-1147101-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044739-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | disclosed |