Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 17/20 | 0.52 |
| ▸ | MMP2 | P08253 | 14/20 | 0.52 |
| ▸ | MMP1 | P03956 | 9/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421799 | 0.92 | MMP9 (0.52) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7430869 | 0.88 | MMP2 (0.49) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7434867 | 0.80 | MMP9 (0.43) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7596470 | 0.79 | MMP9 (0.80) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7596477 | 0.79 | MMP9 (0.80) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7421796 | 0.74 | MMP1 (0.43) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL4429590 | 0.72 | MMP9 (0.37) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7595943 | 0.71 | MMP9 (0.80) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7595948 | 0.71 | MMP9 (0.80) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL7597601 | 0.71 | MMP9 (0.80) | MMP9MMP2MMP1MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000044739-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |