Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPR3 | P17342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809508 | 0.82 | EPHX2 (0.44) | EPHX1THRBEPHX2GAANPR3 | |
| SCHEMBL10080373 | 0.78 | GAA (0.47) | ALDH1A1NPSR1TSHREPHX1L3MBTL1 | |
| SCHEMBL12297319 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1TSHREPHX1L3MBTL1 | |
| SCHEMBL2810319 | 0.77 | NPR3 (0.39) | ALDH1A1EPHX1F2THRBEPHX2 | |
| SCHEMBL7216573 | 0.77 | F2 (0.43) | ALDH1A1NPSR1TSHRF2L3MBTL1 | |
| SCHEMBL1163035 | 0.77 | MMP13 (0.35) | MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL7218526 | 0.76 | F2 (0.43) | ALDH1A1NPSR1TSHRF2L3MBTL1 | |
| SCHEMBL6826213 | 0.76 | CYP1A2 (0.40) | ALDH1A1TSHREPHX1F2MEN1 | |
| SCHEMBL1054142 | 0.74 | REN (0.39) | EPHX1KMT2AEPHX2GAA | |
| SCHEMBL27821171 | 0.74 | REN (0.39) | EPHX1KMT2AEPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |