Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193382 | 0.88 | TSHR (0.60) | TSHRCA12CA14LTA4HKMT2A | |
| SCHEMBL17817739 | 0.86 | TSHR (0.52) | TSHRCA12CA14KMT2AMEN1 | |
| SCHEMBL10667342 | 0.86 | TSHR (0.57) | TSHRCA12CA14LTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL15654082 | 0.84 | TSHR (0.55) | TSHRCA12CA14LTA4HKMT2A | |
| SCHEMBL72889 | 0.83 | TSHR (0.67) | TSHRCA12CA14LTA4HKMT2A | |
| SCHEMBL13969418 | 0.82 | TSHR (0.52) | TSHRCA12CA14LTA4HKMT2A | |
| SCHEMBL7432168 | 0.82 | EPHX2 (0.54) | TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL10056635 | 0.81 | — | — | |
| SCHEMBL7429768 | 0.81 | GAA (0.48) | LTA4HKMT2AEGLN1ALDH1A1MAPT | |
| SCHEMBL12847508 | 0.80 | TSHR (0.63) | TSHRCA12CA14LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-04-20 | — | — | US | disclosed |
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-22 | — | — | US | disclosed |
| US-10745692-B2 | Production method for charged non-protein amino acid-containing peptide | THE UNIVERSITY OF TOKYO (JP) | 2020-08-18 | — | — | US | disclosed |
| US-10682374-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| US-10351593-B2 | Derivatives of dolastatin 10 and uses thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2019-07-16 | — | — | US | disclosed |
| US-20190076462-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-03-14 | — | — | US | disclosed |
| US-20180141973-A1 | Derivatives of Dolastatin 10 and Uses Thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20160289668-A1 | Production Method for Charged Non-Protein Amino Acid-Containing Peptide | THE UNIVERSITY OF TOKYO (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3031915-A1 | PRODUCTION METHOD FOR CHARGED NON-PROTEIN AMINO ACID-CONTAINING PEPTIDE | The University of Tokyo (JP) | 2016-06-15 | — | — | EP | disclosed |
| EP-1834802-B1 | Infrared-sensitive lithographic printing plate | FUJIFILM CORP (JP) | 2009-01-14 | — | — | EP | disclosed |
| EP-1834802-A1 | Infrared-sensitive lithographic printing plate | FUJIFILM Corporation (JP) | 2007-09-19 | — | — | EP | disclosed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | TSHR 315/4885CA12 4164/4885CA14 4400/4885 |
| US-10351593-B2 | Derivatives of dolastatin 10 and uses thereof | PCSK9, DDOST, DHCR7 | TSHR 4727/4885CA12 3795/4885CA14 2728/4885 |
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | TSHR 315/4885CA12 4164/4885CA14 4400/4885 |
| US-20180141973-A1 | Derivatives of Dolastatin 10 and Uses Thereof | PCSK9, DDOST, DHCR7 | TSHR 4727/4885CA12 3795/4885CA14 2728/4885 |
| US-20190076462-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | TSHR 315/4885CA12 4164/4885CA14 4400/4885 |
| US-10682374-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | APLNR, NPPA, ARGLU1 | TSHR 315/4885CA12 4164/4885CA14 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.