Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083527 | 0.89 | RIPK1 (0.40) | RIPK1MMP8OPRK1L3MBTL1MAPT | |
| SCHEMBL7433686 | 0.81 | F2 (0.46) | RIPK1MMP8OPRK1POLB | |
| SCHEMBL8098103 | 0.81 | RIPK1 (0.51) | RIPK1MMP8OPRK1POLBSMN1; SMN2 | |
| SCHEMBL8095454 | 0.80 | MMP8 (0.37) | MMP8L3MBTL1MAPTEPHX2TPSAB1 | |
| SCHEMBL8091532 | 0.78 | MMP8 (0.36) | MMP8L3MBTL1MAPTEPHX2TPSAB1 | |
| SCHEMBL8095158 | 0.78 | MMP8 (0.36) | MMP8L3MBTL1MAPTEPHX2TPSAB1 | |
| SCHEMBL8091531 | 0.77 | MMP8 (0.35) | MMP8L3MBTL1MAPTEPHX2TPSAB1 | |
| SCHEMBL7438276 | 0.75 | F2 (0.38) | RIPK1MMP8OPRK1L3MBTL1MAPT | |
| SCHEMBL7438271 | 0.75 | F2 (0.43) | RIPK1OPRK1 | |
| SCHEMBL8091386 | 0.75 | RIPK1 (0.43) | RIPK1MMP8OPRK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |