Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 16/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447128 | 0.91 | RAB9A (0.52) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7443888 | 0.90 | POLB (0.48) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7447951 | 0.90 | DRD4 (0.50) | DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL7436573 | 0.90 | HTT (0.47) | DRD4DRD2DRD3ALDH1A1RAB9A | |
| SCHEMBL7442150 | 0.88 | DRD4 (0.52) | DRD4ALDH1A1 | |
| SCHEMBL7435451 | 0.87 | RAB9A (0.51) | DRD4ALDH1A1NPC1RAB9A | |
| SCHEMBL7441217 | 0.87 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9A | |
| SCHEMBL7436669 | 0.87 | ALDH1A1 (0.52) | DRD4DRD3ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7444391 | 0.86 | ALDH1A1 (0.52) | DRD4DRD3ALDH1A1NPC1RAB9A | |
| SCHEMBL7429340 | 0.86 | POLB (0.49) | DRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |