Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436669 | 0.93 | ALDH1A1 (0.52) | RAB9ANPC1LMNAPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7444391 | 0.92 | ALDH1A1 (0.52) | RAB9ANPC1LMNAPOLBALDH1A1 | |
| Acetic Acid SCHEMBL7435033 | 0.91 | ALDH1A1 (0.50) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL7431672 | 0.89 | LMNA (0.53) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL7447128 | 0.89 | RAB9A (0.52) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL7439962 | 0.88 | ALDH1A1 (0.47) | RAB9ANPC1LMNAALDH1A1DRD4 | |
| SCHEMBL7434584 | 0.88 | ALDH1A1 (0.47) | RAB9ANPC1LMNAALDH1A1DRD4 | |
| SCHEMBL7433767 | 0.87 | DRD4 (0.53) | RAB9ANPC1ALDH1A1DRD4 | |
| SCHEMBL7437173 | 0.87 | ALDH1A1 (0.49) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL10991013 | 0.87 | ALOX15 (0.51) | RAB9ANPC1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |