Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436643 | 0.86 | SLC7A5 (0.51) | MMECTRB1 | |
| SCHEMBL7441034 | 0.86 | ACACB (0.51) | ACACBPPARGPPARACTRB1MEN1 | |
| SCHEMBL7434134 | 0.86 | CTRB1 (0.55) | CYP1A2CTRB1CTSSCTSKNPC1 | |
| SCHEMBL7442013 | 0.86 | CTRB1 (0.55) | CYP1A2CTRB1CTSSCTSKNPC1 | |
| SCHEMBL7444226 | 0.85 | ALDH1A1 (0.44) | PPARGPPARACTRB1CTSSCTSK | |
| SCHEMBL7436512 | 0.84 | ACACB (0.53) | ACACBPPARGPPARACTRB1 | |
| SCHEMBL7438864 | 0.84 | ACACB (0.56) | ACACBMMECTRB1 | |
| SCHEMBL7432787 | 0.82 | LDHA (0.58) | ACACBPPARGPPARAFPR2KMT2A | |
| SCHEMBL7439954 | 0.82 | LDHA (0.58) | ACACBPPARGPPARAFPR2KMT2A | |
| SCHEMBL7438493 | 0.81 | ALDH1A1 (0.46) | ACACBPPARANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |