Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.56 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 13/20 | 0.51 |
| ▸ | ACE | P12821 | 12/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.51 |
| ▸ | CPA1 | P15085 | 6/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.47 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442013 | 0.91 | CTRB1 (0.55) | CTRB1 | |
| SCHEMBL7434134 | 0.91 | CTRB1 (0.55) | CTRB1 | |
| SCHEMBL7436643 | 0.85 | SLC7A5 (0.51) | MMEACEACE2CPA1CTRB1 | |
| SCHEMBL7441034 | 0.85 | ACACB (0.51) | ACACBCTRB1 | |
| SCHEMBL7444226 | 0.84 | ALDH1A1 (0.44) | ACECPA1CTRB1 | |
| SCHEMBL7434156 | 0.84 | ACACB (0.52) | ACACBMMECTRB1 | |
| SCHEMBL7436512 | 0.82 | ACACB (0.53) | ACACBCTRB1 | |
| SCHEMBL7436981 | 0.82 | TACR1 (0.51) | ACACBMMEACEACE2CPA1 | |
| SCHEMBL6436295 | 0.81 | MME (0.68) | ACACBMMEACEACE2CPA1 | |
| SCHEMBL6857632 | 0.81 | MME (0.68) | ACACBMMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |