Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429906 | 0.88 | CTSK (0.49) | CTSSCTSKBACE1ATMREN | |
| SCHEMBL7445430 | 0.87 | BACE1 (0.40) | GAACTSSCTSKBACE1CA1 | |
| SCHEMBL7431998 | 0.85 | L3MBTL1 (0.46) | GAACTSSCTSKBACE1PPARA | |
| SCHEMBL7441219 | 0.80 | POLB (0.46) | CTSKATM | |
| SCHEMBL7433454 | 0.80 | CTSK (0.55) | GAACTSSCTSKPPARAPPARG | |
| SCHEMBL7438946 | 0.77 | MAPT (0.42) | CTSSCTSKPSMB1 | |
| SCHEMBL7438051 | 0.76 | CA1 (0.41) | GAACTSSCTSKCA1CA2 | |
| SCHEMBL17107013 | 0.76 | BACE1 (0.55) | CTSSCTSKBACE1 | |
| SCHEMBL17107011 | 0.76 | BACE1 (0.55) | CTSSCTSKBACE1 | |
| SCHEMBL17107008 | 0.76 | BACE1 (0.55) | CTSSCTSKBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |