Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429906 | 0.88 | CTSK (0.49) | BACE1CTSKCTSSATM | |
| SCHEMBL7434164 | 0.87 | GAA (0.40) | BACE1CA1CA2CTSKCTSS | |
| SCHEMBL7431998 | 0.87 | L3MBTL1 (0.46) | BACE1CA1CA2CTSKCTSS | |
| SCHEMBL7441219 | 0.82 | POLB (0.46) | EPHX2CTSKALDH1A1LMNAATM | |
| SCHEMBL7435956 | 0.80 | CTSK (0.55) | EPHX2NR1H4ABCB1CTSKCTSS | |
| SCHEMBL7438946 | 0.77 | MAPT (0.42) | CTSKCTSSALDH1A1 | |
| SCHEMBL11957489 | 0.76 | L3MBTL1 (0.53) | EPHX2NR1H4CA1CA2GAA | |
| SCHEMBL7438051 | 0.76 | CA1 (0.41) | CA1CA2CTSKCTSSGAA | |
| SCHEMBL17107013 | 0.76 | BACE1 (0.55) | BACE1CTSKCTSS | |
| SCHEMBL17107011 | 0.76 | BACE1 (0.55) | BACE1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |