Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431998 | 0.89 | L3MBTL1 (0.46) | MEN1KMT2ACTSSCTSKALDH1A1 | |
| SCHEMBL7441219 | 0.86 | POLB (0.46) | SMN1; SMN2MEN1KMT2ACTSKALDH1A1 | |
| SCHEMBL7429906 | 0.84 | CTSK (0.49) | KLK5CTSSCTSK | |
| SCHEMBL7449272 | 0.82 | CTSK (0.52) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1019102 | 0.80 | MAPT (0.55) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7438937 | 0.78 | OPRM1 (0.43) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7445430 | 0.77 | BACE1 (0.40) | CTSSCTSKALDH1A1 | |
| SCHEMBL7434164 | 0.77 | GAA (0.40) | PSMB1CTSSCTSK | |
| SCHEMBL28096705 | 0.75 | MAPT (0.50) | MAPTALOX5CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10521504 | 0.74 | KLK5 (0.58) | MAPTALOX5CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |