Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442355 | 0.88 | CTSK (0.71) | CTSKPPARACTSSPPARGCTSL | |
| SCHEMBL7435956 | 0.87 | CTSK (0.55) | CTSKPPARACTSSPPARGGAA | |
| SCHEMBL7440842 | 0.84 | CTSK (0.53) | CTSKPPARACTSSPPARGGAA | |
| SCHEMBL7434164 | 0.80 | GAA (0.40) | CTSKPPARACTSSPPARGGAA | |
| SCHEMBL7443191 | 0.79 | CTSK (0.54) | CTSKCTSSCACNA1B | |
| SCHEMBL7449272 | 0.77 | CTSK (0.52) | CTSKPPARACTSSPPARG | |
| SCHEMBL7433111 | 0.76 | CTSK (0.49) | CTSKPPARACTSSPPARGCTSL | |
| SCHEMBL7445934 | 0.75 | CTSK (0.54) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7437324 | 0.74 | CTSK (0.33) | CTSKGAA | |
| SCHEMBL7437313 | 0.74 | CTSK (0.33) | CTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |