Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435500 | 0.82 | ALDH1A1 (0.57) | LMNAALDH1A1MEN1KMT2ADRD4 | |
| SCHEMBL7289700 | 0.82 | KDM4E (0.62) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| SCHEMBL7442119 | 0.81 | RAB9A (0.48) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7525895 | 0.81 | KDM4E (0.61) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| SCHEMBL7445611 | 0.79 | POLB (0.59) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7434820 | 0.77 | ALDH1A1 (0.68) | KDM4ELMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7437717 | 0.77 | DGAT1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7446265 | 0.77 | TDP1 (0.56) | KDM4ELMNAALDH1A1RAB9AMEN1 | |
| SCHEMBL7432879 | 0.74 | ALDH1A1 (0.48) | KDM4ELMNAALDH1A1MAPTNPC1 | |
| SCHEMBL9031046 | 0.74 | DRD4 (0.60) | KDM4ELMNAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |